Polycystic ovarian syndrome is a disease with dysgenesis and metabolic disorders, which has the characteristics including the polycystic ovary and hyperandrogenism. In order to guide the diagnose the syndrome, three visions of diagnostic criteria were presented and implemented all over the world, the National Institutes of Health 1990 criteria, the Rotterdam 2003 criteria, and the Androgen Excess Society 2006 criteria. Many adipokines have effects on PCOS, which have the following biological fuctions, such as inflammatory response, immunoreaction, energy storage, and so on. Chemerin, a new adipokine, was found with higher concentration in PCOS patients, comparing the healthy, therole of which in the pathogenesis of PCOS was not clear. This review indicated the role of Chemerin in the pathological development which maintain the potential therapeutic target in PCOS.